Chondriotin Sulfate Combats Brain & Mental Health Diseases

Brain and mental health

The post-mortem analysis of the brains of schizophrenics when compared to normal brains reveals severe dysregulation in the matrix outside of brain cells that hold them together in important regions of the subconscious brain (associated with memory, learning and the processing of stress). The finding is the first of its kind and essentially it means that the “roads and highways” that hold brain cells in position are at least as important as the neurotransmitter status, that up to now, has received most of the attention.

The researchers studied the chondroitin sulfate structure of the important matrix between brain cells that enables the actual structure of a part of the brain. They concentrated on looking at two important brain regions, the entorhinal cortex (behavior and memory) and the amygdala (anxiety, compulsions, hostility, stress response). They discovered that the glial cells expressed up to 15 fold normal activity with chondroitin sulfate. This means that the brain of those patients with schizophrenia were trying desperately to repair their cellular matrix and restore brain function, an attempt that clearly was not working, although ongoing. This can be concluded by the fact that these brain area's physical mass, as compared to controls, was less than normal.

Since glial cells regulate both brain repair and brain inflammation, it is obvious that significant mental problems involve excessive inflammation with a lack of repair. Something is getting in their way, even if the glial cells are trying to make a repair.

This study is relevant to everyone as it is likely that part of the lessening of nervous system function involves glial cell interaction with the chondroitin sulfate rich structure of the cellular matrix between brain cells. Therefore it can be said that any level of mental health issues ranging from ADHD to depression to anxiety, and nerve transmission problems will have at least part of the problem the structural integrity of the brain cell matrix, directly affecting synaptic plasticity and overall brain health.
Chondroitin sulfate benefits

A lot of people already know that chondroitin sulfates are good for their joints, as a matter of fact it is used as an alternative medicine to treat osteoarthritis. However fewer seem to understand that they are vital for the healthy structure of their arteries. While this story is still at its beginning, they may actually turn out to be vital to mental health! To be sure, any solution that facilitates the restoring of the physical structure of the brain and the proper structural framework of any one brain part is going to be more likely to lend to better overall connectivity and fewer mental health issues.
Side effects of chondroitin sulfate

Side effects are usually mild. The most common complaints are gas, indigestion, nausea, heartburn and softening of the stool.